IsoPure™ Mini, Automated Purification System

Magnetic bead-based purification has become a preferred method for isolating DNA, RNA, and other target molecules from a variety of biological sample types. The quality and quantity of the extracted molecules can be significantly higher than other methods, such as spin columns, while the cost per sample can be lower. The IsoPure™ Mini from Accuris Instruments is a compact, automated purification system that improves efficiency and reproducibility using the magnetic bead-based method. Capable of processing up to 16 samples at one time, the instrument is easy to set up, program, and operate. Mixing, magnetic bead transfer, washing, and elution steps are performed automatically, saving valuable hands-on time. The purification process can be completed within 10 to 60 minutes depending on the type of reagent kit used and the complexity of the program.

Programming via Android™ App or PC Software - Creating a protocol is simple using the IsoPure app or PC software, both are included on a USB flash drive with each instrument. Mixing speed, sample temperature, and magnetization parameters can be all be programmed. Protocols created using the IsoPure app can be transferred to the instrument via Bluetooth connection. Protocols created using the PC software can be transferred to the instrument via USB connection. In addition, both the IsoPure app and PC software can generate a protocol-specific QR code for instant transfer.

QR code Scanning System - A handheld scanner is included with each IsoPure Mini, adding a convenient and fast method for loading a protocol onto the instrument. After creating or opening a protocol on a companion Android device or a connected PC, an option is available for displaying a QR code. Simply scan the QR code to instantly transfer the protocol. QR codes are also available in kit instruction manuals for instant loading of optimized protocol.

Sample Temperature Control - Heating sample mixtures during the lysis and elution steps can significantly improve results. Heating strips on the sample platform can be precisely set to any temperature between ambient +5°C to 120°C. Both deep well plates and 6-well reagent vessels fit into the contoured heating strips for efficient heat transfer. Two cooling fans maintain ambient temperature inside the housing and temperature of the heating strips.

Touch-Screen Control Panel - The control panel on top of the IsoPure Mini allows for quick selection of stored protocols and instrument control. To execute a protocol, select it from the file list, insert a prepared sample plate (or 6-well reagent vessel) and tip combs, and press the start button. Run parameters and operating status are displayed during sample processing.

IsoPure™ Consumables - Accuris offers magnetic tip combs, deep well plates, and 6-well sample strips designed to fit the IsoPure Mini. Produced using virgin polypropylene and packaged in a sterile environment, these consumables are guaranteed to be contaminant-free. The 8-place magnetic tip combs lock into position inside the instruments processing chamber. There are 2 options for sample vessels: 96 deep-well plates can be used for processing up to 16 samples. For 8 or fewer samples, 6-well sample strips can be used, and these are loaded onto the included aluminum rack. These sample strips reduce waste and lower consumable costs when only a few samples need to be processed.