The Quick-RNA MagBead kit provides a high-throughput, magnetic bead-based purification of high-quality total RNA (including small/microRNAs) from any sample source (e.g., cells, solid tissue, whole blood, biological fluids, FFPE tissue, environmental (plant/seed), swabs (stool, soil, microbial samples)), samples stored in DNA/RNA Shield, etc. The provided DNA/RNA Shield inactivates infectious agents and is ideal for sample storage at ambient temperatures. Total RNA is eluted into ≥50 µl of DNase/RNase-Free Water and is ready for any downstream application including Next-Gen Sequencing, RT/PCR, hybridization, etc.