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Precision System Science

geneLEAD VIII, Sample-to-Answer Molecular Diagnostic Instrument, 120/240 V

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geneLEAD VIII, Sample-to-Answer Molecular Diagnostic Instrument, 120/240 V

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Sample to Result
The geneLEAD VIII has three operational modes for versatile sample processing; Complete nucleic acid extraction combined with PCR/nucleic acid extraction only/PCR only. GeneLEAD VIII software allows the programming and storage of user-specific PCR protocols.

Instrument Flexibility
The geneLEAD VIII utilizes MagDEA Dx extraction reagents optimized for total nucleic acids or total RNA from a variety of sample types. A maximum of eight samples can be processed in parallel, while the PCR program can be selected individually for each sample. Real-time PCR is performed in eight independently controlled thermal cyclers with fluorescence detection across six different channels

User-Friendly Operation
The geneLEAD VIII is operated from an external PC and can be connected to the central server using a dedicated LIMS compatible software. Prefilled, ready-to-use, reagent cartridges simplify user setup and waste management. The software guides and prompts the user to ensure a proper and valid test setup. Onboard barcode and QR code reading ensure traceability and integrity of samples, controls, and reagents.

Safety Considerations
geneLEAD VIII was designed with today’s laboratory safety concerns in mind. The instrument is equipped with a HEPA filter to remove airborne contaminants during testing and a UV decontamination lamp for post-process sterilization.

The geneLEAD VIII is a fully automated, sample-to-result precision instrument. The instrument utilizes magDEA Dx SV magnetic bead chemistry for total nucleic acid extraction and is open-platform for user specified qPCR or other other detection analysis. Samples, reagents and consumables are placed in the instrument and the assay is started. The instrument is open platform for qPCR and other Upon completion the nucleic acids are transferred to the PCR well, and the PCR master mix is added and qPCR thermal cycling started. Results are analyzed and reported directly by the instrument and can be accessed remotely using LIMS system.

A2700genLEAD VIII 
FeaturesSample Volume200 µL
 Elution Volume20 to 50 µL
 PCR Volumeup to 50 µL
 Processing TimeDNA Extraction – 30 min 
 PCR-Thermal cycling protocol dependent
 OperationCan be used in one of three modes. Sample-to-Answer, Extraction only or qPCR only.
 Themal cyclingEight independently controlled thermal cyclers. 
 Capable of running eight different thermal cycling protocols or eight identical thermal cycling protocols. 
 Fluorsent monitoringCompatible with the following dyes:
 Contamination ControlFully automated enclosed system with a dedicated lane for each sample, sealed prefilled walled reagent cartridges, HEPA filtered, UV light decontamination.
 ReagentsmagDEA Dx SV and magDEA Dx SV RNA
 PCR reagents are user supplied and can be either liquid or lyophilized.
   
SpecificationsInstrument TypeBenchtop Molecular Testing: Sample-to-Answer
 Dimensions350W × 700D × 770H mm (14W × 28D × 30H inches)
 Weight80 kg. (180 lbs.)
 PowerAC100-240V ±10%, 50/60Hz, 300VA
 Number of samples1 to 8
 Sample Extraction time200 µL: 27 min
 Pipetting0.5 to 25mL
 Protocol – Extraction MagDEA Dx SV reagents and protocol
 Protocol – PCRCustomer defined applications.
 Spectrometer6 Fluorescent Channels: dye specific LED excitation, photo diode emission detection.
 Channel 1: FAM           Channel 2: HEX
 Channel 3: ROX           Channel 4: TAMRA
 Channel 5: Cy5            Channel 6: Cy5.5
  
 Temperature – Extraction Heat Block65 to 80 °C
 Temperature – Thermal CyclerTemperature Range: 40 to 99 °C 
 Thermal Ramp Rate: 3.4°C / sec. 
 Accuracy: ± 0.3°C (60 -95 °C)
 LIMS compatabilityYes

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Product Detail
Thomas No.
22A00H942
Mfr. No.
A2700
Description
geneLEAD VIII, Sample-to-Answer Molecular Diagnostic Instrument, 120/240 V
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